After the Marvel fictional government agency, it shows that not all were superheroes.

Fil Koulson (Avengers), to recruit a new team going into the field for the treatment of all cases, extraordinary and wonderful. Field turned table Jockey Agent Melinda May and British scientist Gemma Simmons and Leo Fitz travelwith him solo Agent Grant Ward Feld. Coulson to work quickly civilian computer hacker known only as Skye, an unknown woman with a secret past.